Set in the bustling Manhattan of Damon Runyon's short stories, Guys and Dolls is a Depression era romantic comedy featuring crap games, horse races, gamblers, show girls and the evangelist members of a downtown Mission.

Con-man Nathan Detroit is seeking a new location for his notorious 'floating' crap game, but he doesn't have the dough he needs for a down payment. Enter Sky Masterson, a high-rolling gambler willing to take on any honest bet with a high enough reward attached. Nathan bets Sky that he can’t take the “doll”, of Nathan’s choosing, on a date to Havana, Cuba. When Sky agrees to the bet, Nathan chooses uptight Evangelist Sergeant Sarah Brown, head of Broadway’s Save-a-Soul Mission. Sky thinks he’s been duped, but he’s in for even more of a surprise when his efforts to woo Sarah are so successful that he falls in love with her himself! Meanwhile Nathan is under pressure from his long time 'fiancee' and night club dancer, Miss Adelaide, to settle down and get married. What are the odds?